Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 2/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 11/20 | 0.36 |
| ▸ | IL1B | P01584 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.35 |
| ▸ | CCNK | O75909 | 2/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.35 |
| ▸ | CDK2 | P24941 | 2/20 | 0.35 |
| ▸ | CDK9 | P50750 | 2/20 | 0.35 |
| ▸ | CDK12 | Q9NYV4 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.34 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.34 |
| ▸ | ITK | Q08881 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30833937 | 0.86 | NLRP3 (0.45) | NLRP3IL1BROCK2ROCK1 | |
| SCHEMBL25302097 | 0.84 | KAT2B (0.39) | NLRP3IL1BCCNT1CCNKCCNE1 | |
| SCHEMBL25302099 | 0.84 | KAT2B (0.39) | NLRP3IL1BCCNT1CCNKCCNE1 | |
| SCHEMBL30833928 | 0.81 | KAT2B (0.33) | NLRP3CCNT1CCNKCCNE1CDK2 | |
| SCHEMBL24695417 | 0.75 | CAMK2D (0.41) | CAMK2DNLRP3IL1BKCNH2CCNT1 | |
| SCHEMBL24695702 | 0.75 | CAMK2D (0.45) | CAMK2DNLRP3IL1BKCNH2ITK | |
| SCHEMBL29159546 | 0.75 | CAMK2D (0.45) | CAMK2DNLRP3IL1BKCNH2ITK | |
| SCHEMBL30488557 | 0.74 | BTK (0.49) | — | |
| SCHEMBL30833987 | 0.72 | NLRP3 (0.56) | CAMK2DNLRP3IL1BKCNH2CCNT1 | |
| SCHEMBL31367803 | 0.72 | NLRP3 (0.57) | CAMK2DNLRP3IL1BKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4613749-A1 | NLRP3 INFLAMMASOME INHIBITOR AND USE THEREOF | TransThera Sciences (Nanjing), Inc. (CN) | 2025-09-10 | — | — | EP | disclosed |
| CN-117986258-A | NLRP3 inflammation corpuscle inhibitor and application thereof | 药捷安康(南京)科技股份有限公司 | 2024-05-07 | — | — | CN | disclosed |