SCHEMBL30834278

SCHEMBL30834278

Cc1ccc2c(c1C)CC(C)(CO)C2=O

nearest known ligand 0.36

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
EED O75530 1/20 0.36
SUZ12 Q15022 1/20 0.36
EZH2 Q15910 1/20 0.36
TDP2 O95551 1/20 0.35
NSD2 O96028 1/20 0.35
HSP90AA1 P07900 1/20 0.35
PAX8 Q06710 1/20 0.35
KDM4E B2RXH2 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
POLB P06746 1/20 0.33
RECQL P46063 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
KCNJ1 P48048 4/20 0.30
KCNH2 Q12809 4/20 0.30
ACHE P22303 1/20 0.30
SSTR1 P30872 1/20 0.30
SLC6A4 P31645 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20584661 1.00 EED (0.36) EEDSUZ12EZH2TDP2NSD2
SCHEMBL7184848 0.81 ALDH1A1 (0.44) EEDSUZ12EZH2KDM4EALDH1A1
SCHEMBL17926681 0.80 MAPT (0.39) TDP2NSD2HSP90AA1PAX8ALDH1A1
SCHEMBL31012294 0.71 CA1 (0.42) KDM4EALDH1A1ACHE
SCHEMBL7191025 0.71 CA1 (0.42) KDM4EALDH1A1ACHE
SCHEMBL7188817 0.70 HTT (0.51) EEDSUZ12EZH2ALDH1A1
SCHEMBL8076792 0.68 HTT (0.47) KDM4EALDH1A1HPGDPOLBNPSR1
SCHEMBL7187309 0.68 METAP1 (0.42) KDM4EHPGDACHE
SCHEMBL31012318 0.68 METAP1 (0.42) KDM4EHPGDACHE
SCHEMBL7190214 0.65 CA1 (0.40) EEDSUZ12EZH2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117797295-A Indane derivatives for malodor counteracting 弗门尼舍有限公司 2024-04-02 CN disclosed