SCHEMBL7184848

SCHEMBL7184848

Cc1cccc2c1CC(C)(CO)C2=O

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.44
KDM4E B2RXH2 2/20 0.43
LMNA P02545 1/20 0.42
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
CA7 P43166 1/20 0.40
CA9 Q16790 1/20 0.40
ACHE P22303 1/20 0.39
PARP1 P09874 1/20 0.38
PARP10 Q53GL7 1/20 0.38
PARP11 Q9NR21 1/20 0.38
TP53 P04637 1/20 0.35
GAA P10253 2/20 0.34
DAO P14920 1/20 0.34
MAPT P10636 1/20 0.34
RAB9A P51151 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
EED O75530 1/20 0.34
SUZ12 Q15022 1/20 0.34
EZH2 Q15910 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12086607 0.83 ALDH1A1 (0.43) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL20584661 0.81 EED (0.36) ALDH1A1KDM4EACHEEEDSUZ12
SCHEMBL30834278 0.81 EED (0.36) ALDH1A1KDM4EACHEEEDSUZ12
SCHEMBL17926633 0.80 ALDH1A1 (0.41) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL11931726 0.78 ALDH1A1 (0.42) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL12261408 0.78 ALDH1A1 (0.50) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL27952596 0.75 ALDH1A1 (0.47) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL8076792 0.75 HTT (0.47) ALDH1A1KDM4ELMNAGAAMAPT
SCHEMBL7190214 0.74 CA1 (0.40) ALDH1A1KDM4ELMNACA1CA2
SCHEMBL25002993 0.73 ALDH1A1 (0.45) ALDH1A1KDM4ELMNACA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022265-B1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH & CIE (CH) 2003-03-26 EP claimed
US-6323173-B1 COMPOUNDS WHICH DEVELOP FRESH, HUMIC, VERY PLEASANT FRAGRANCE OF LILY OF THE VALLEY TYPE; GOOD STABILITY AND EXCELLENT TENACITY FIRMENICH SA (CH) 2001-11-27 US claimed
EP-1022265-A1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH SA (CH) 2000-07-26 EP claimed