SCHEMBL8076792

SCHEMBL8076792

CC1(CO)Cc2ccccc2C1=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 3/20 0.47
NPSR1 Q6W5P4 2/20 0.47
LMNA P02545 2/20 0.47
L3MBTL1 Q9Y468 2/20 0.47
GAA P10253 4/20 0.47
KDM4E B2RXH2 4/20 0.47
PRNP P04156 2/20 0.43
PPARG P37231 2/20 0.43
RXFP1 Q9HBX9 2/20 0.43
NCOR2 Q9Y618 2/20 0.43
NR2E3 Q9Y5X4 1/20 0.43
ALDH1A1 P00352 4/20 0.42
KMT2A Q03164 2/20 0.41
HPGD P15428 1/20 0.41
MAPT P10636 2/20 0.41
RAB9A P51151 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
POLB P06746 1/20 0.40
PKM P14618 1/20 0.39
MEN1 O00255 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11528017 0.84 KDM4E (0.63) HTTNPSR1LMNAL3MBTL1GAA
SCHEMBL12086597 0.81 GAA (0.49) HTTNPSR1LMNAL3MBTL1GAA
SCHEMBL23397542 0.80 LMNA (0.43) HTTNPSR1LMNAL3MBTL1GAA
SCHEMBL12086636 0.79 NPSR1 (0.45) HTTNPSR1LMNAL3MBTL1GAA
SCHEMBL12086639 0.78 ALOX12 (0.55) HTTNPSR1LMNAL3MBTL1GAA
SCHEMBL31012294 0.78 CA1 (0.42) HTTGAAKDM4EALDH1A1SMN1; SMN2
SCHEMBL7191025 0.78 CA1 (0.42) HTTGAAKDM4EALDH1A1SMN1; SMN2
SCHEMBL7187309 0.78 METAP1 (0.42) HTTKDM4EHPGD
SCHEMBL31012318 0.78 METAP1 (0.42) HTTKDM4EHPGD
SCHEMBL15630925 0.78 LMNA (0.64) HTTNPSR1LMNAL3MBTL1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1022265-A1 2-Indanemethanol derivatives and their use as perfuming ingredients FIRMENICH SA (CH) 2000-07-26 EP disclosed