SCHEMBL30834458

SCHEMBL30834458

Cc1cc(F)c(-n2ccc(C(F)(F)F)n2)nc1Cc1cccc(C(F)(F)F)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.39
CYP3A4 P08684 1/20 0.39
CYP2D6 P10635 1/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
MAPT P10636 1/20 0.38
NPY5R Q15761 1/20 0.37
GPR52 Q9Y2T5 4/20 0.36
TAAR1 Q96RJ0 1/20 0.36
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
PRMT6 Q96LA8 1/20 0.35
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
HTR2B P41595 1/20 0.34
LTA4H P09960 1/20 0.34
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
KCNN4 O15554 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30834460 1.00 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL30834450 0.87 CYP1A2 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5209985 0.81 HSP90AA1 (0.39) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL5202428 0.73 MEN1 (0.38) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL30834453 0.70 P2RY1 (0.41) CYP1A2CYP2C9CYP2C19MAPTMEN1
SCHEMBL30834440 0.69 KMT2A (0.47) CYP1A2CYP3A4CYP2C9CYP2C19MAPT
SCHEMBL25314609 0.69 CCR2 (0.38) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL30465885 0.69 CCR2 (0.38) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19
SCHEMBL30834449 0.68 ABCG2 (0.41) CYP1A2CYP2C9CYP2C19KDM4EALDH1A1
SCHEMBL5207531 0.66 RAB9A (0.46) CYP1A2CYP3A4CYP2D6CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024072768-A1 SUBSTITUTED FLUOROPYRIDINE AS HERBICIDES FMC CORPORATION (US) 2024-04-04 WO disclosed