Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM7 | Q14831 | 1/20 | 0.32 |
| ▸ | KRAS | P01116 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21722189 | 1.00 | GRM7 (0.32) | GRM7KRASSRCADRA1A | |
| SCHEMBL21734011 | 0.73 | KRAS (0.41) | GRM7KRAS | |
| SCHEMBL21722231 | 0.73 | KRAS (0.41) | GRM7KRAS | |
| SCHEMBL30834506 | 0.73 | KRAS (0.41) | GRM7KRAS | |
| SCHEMBL20836477 | 0.72 | GRM7 (0.46) | GRM7ADRA1A | |
| SCHEMBL31483708 | 0.72 | GRM7 (0.46) | GRM7ADRA1A | |
| SCHEMBL21722290 | 0.72 | MAPT (0.36) | — | |
| SCHEMBL21733758 | 0.72 | KMT2A (0.39) | — | |
| SCHEMBL24854593 | 0.72 | GRM7 (0.43) | GRM7KRAS | |
| SCHEMBL21734020 | 0.72 | GRM7 (0.33) | GRM7KRAS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112119075-B | Condensed ring compound | 豪夫迈·罗氏有限公司 | 2024-03-12 | — | — | CN | disclosed |