Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | JAK2 | O60674 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | STAT5B | P51692 | 1/20 | 0.33 |
| ▸ | JAK3 | P52333 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18109302 | 1.00 | PIK3CD (0.51) | PIK3CDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL29929823 | 0.78 | EGLN2 (0.42) | PIK3CDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL186339 | 0.78 | EGLN2 (0.42) | PIK3CDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL11614947 | 0.78 | PIK3CD (0.55) | PIK3CDALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL23482028 | 0.76 | PIK3CD (0.34) | PIK3CDALDH1A1GRM5JAK2NTRK1 | |
| SCHEMBL30677789 | 0.76 | PIK3CD (0.34) | PIK3CDALDH1A1GRM5JAK2NTRK1 | |
| SCHEMBL19709312 | 0.76 | PIK3CA (0.31) | PIK3CDGRM5 | |
| SCHEMBL384105 | 0.75 | KEAP1 (0.38) | PIK3CDALDH1A1MEN1KMT2AGRM5 | |
| SCHEMBL1976471 | 0.75 | ABL1 (0.35) | PIK3CDALDH1A1GRM5JAK2NTRK1 | |
| SCHEMBL22905389 | 0.75 | PIK3CD (0.56) | PIK3CDALDH1A1MEN1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114149409-B | (hetero) aryl amide compound with protein kinase inhibition activity | 中国药科大学 | 2024-03-22 | — | — | CN | disclosed |