Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNE2 | O96020 | 2/20 | 0.71 |
| ▸ | CDK4 | P11802 | 2/20 | 0.71 |
| ▸ | CCND1 | P24385 | 2/20 | 0.71 |
| ▸ | CCNE1 | P24864 | 2/20 | 0.71 |
| ▸ | CDK2 | P24941 | 2/20 | 0.71 |
| ▸ | PIM1 | P11309 | 3/20 | 0.67 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.67 |
| ▸ | PRKCA | P17252 | 2/20 | 0.65 |
| ▸ | PRKACA | P17612 | 1/20 | 0.65 |
| ▸ | PRKACG | P22612 | 1/20 | 0.65 |
| ▸ | PRKACB | P22694 | 1/20 | 0.65 |
| ▸ | GSK3B | P49841 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CASK | O14936 | 1/20 | 0.64 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.64 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.64 |
| ▸ | CCNK | O75909 | 1/20 | 0.64 |
| ▸ | STK10 | O94804 | 1/20 | 0.64 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30834690 | 0.91 | CAMK2D (0.61) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30834705 | 0.89 | CCNE2 (0.62) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL8161998 | 0.89 | PIM1 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30834702 | 0.89 | PIM1 (0.69) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL28101197 | 0.89 | CCNE2 (0.53) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30834694 | 0.89 | PRKCA (0.64) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30834696 | 0.88 | CCNE2 (0.58) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30319793 | 0.87 | PIM1 (0.73) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL5688241 | 0.87 | PIM1 (0.73) | CCNE2CDK4CCND1CCNE1CDK2 | |
| SCHEMBL30834692 | 0.86 | CCNT1 (0.56) | CCNE2CDK4CCND1CCNE1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117886799-A | Protein degradation targeting chimeric compound for targeting degradation of GSK-3 beta and application thereof | 浙江工业大学 | 2024-04-16 | — | — | CN | disclosed |