SCHEMBL308358

SCHEMBL308358

O=C(c1ccccc1)c1cccc2c1C(=O)c1ccccc1C2=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.71
L3MBTL1 Q9Y468 2/20 0.71
MAPT P10636 6/20 0.61
LMNA P02545 5/20 0.61
MEN1 O00255 5/20 0.58
KMT2A Q03164 5/20 0.58
MAPK1 P28482 3/20 0.58
HTT P42858 2/20 0.58
NPSR1 Q6W5P4 2/20 0.58
APAF1 O14727 1/20 0.58
CASP3 P42574 1/20 0.58
SENP8 Q96LD8 1/20 0.58
SENP7 Q9BQF6 1/20 0.58
SENP6 Q9GZR1 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
KEAP1 Q14145 3/20 0.54
NFE2L2 Q16236 1/20 0.54
KDM4E B2RXH2 2/20 0.54
HKDC1 Q2TB90 2/20 0.54
HPGD P15428 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27360880 0.89 ALDH1A1 (0.75) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL9511803 0.87 MAPT (0.59) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL28750153 0.87 ALDH1A1 (0.58) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL27584329 0.84 ALDH1A1 (0.55) ALDH1A1L3MBTL1MAPTLMNAKEAP1
SCHEMBL4403630 0.83 KEAP1 (0.57) ALDH1A1L3MBTL1MAPTLMNAMEN1
Anthraquinone SCHEMBL8941397 0.83 ALDH1A1 (1.00) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL461660 0.83 ALDH1A1 (1.00) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL8931072 0.83 MAPT (0.50) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL11849832 0.83 MAPT (0.54) ALDH1A1L3MBTL1MAPTLMNAMEN1
SCHEMBL28923230 0.83 MAPT (0.55) ALDH1A1L3MBTL1MAPTLMNAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2059267-B1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS NOVARTIS AG (CH) 2012-04-18 EP disclosed
US-8091568-B2 Temporal photo-bleaching of colored lens care solutions and use thereof NOVARTIS AG (CH) 2012-01-10 US disclosed
US-8062607-B2 Lens care methods and kits NOVARTIS AG (CH) 2011-11-22 US disclosed
EP-2049163-B1 LENS CARE METHODS AND KITS NOVARTIS AG (CH) 2010-04-28 EP disclosed
US-20090324466-A1 Lens care methods and kits ALCON INC. (CH) 2009-12-31 US disclosed
US-20090199878-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF ALCON INC. (CH) 2009-08-13 US disclosed
EP-2059267-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF Novartis AG (CH) 2009-05-20 EP disclosed
EP-2049163-A1 LENS CARE METHODS AND KITS Novartis AG (CH) 2009-04-22 EP disclosed
WO-2008021349-A1 TEMPORAL PHOTO-BLEACHING OF COLORED LENS CARE SOLUTIONS AND USE THEREOF NOVARTIS AG (CH) 2008-02-21 WO disclosed
WO-2008008525-A1 LENS CARE METHODS AND KITS NOVARTIS AG (CH) 2008-01-17 WO disclosed
US-4912012-A Photosensitive recording medium capable of image contrast adjustment, and image transfer system operable with the same BROTHER KOGYO KABUSHIKI KAISHA (JP) 1990-03-27 US disclosed
US-4806446-A Photosensitive recording medium capable of image contrast adjustment BROTHER KOGYO KABUSHIKI KAISHA (JP) 1989-02-21 US disclosed