SCHEMBL8931072

SCHEMBL8931072

Nc1ccc2c(c1C(=O)c1ccccc1)C(=O)c1cccc(C(=O)c3ccccc3)c1C2=O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 7/20 0.50
ALDH1A1 P00352 6/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
GAA P10253 1/20 0.50
LMNA P02545 4/20 0.46
MEN1 O00255 4/20 0.46
KMT2A Q03164 4/20 0.46
MAPK1 P28482 3/20 0.46
HTT P42858 2/20 0.46
APAF1 O14727 1/20 0.46
CASP3 P42574 1/20 0.46
NPSR1 Q6W5P4 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46
SENP6 Q9GZR1 1/20 0.46
TDP1 Q9NUW8 1/20 0.46
POLB P06746 3/20 0.46
THRB P10828 1/20 0.46
RECQL P46063 1/20 0.46
MAOA P21397 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11518209 0.96 ALDH1A1 (0.49) MAPTALDH1A1L3MBTL1GAALMNA
SCHEMBL11742792 0.88 MAOA (0.57) MAPTALDH1A1L3MBTL1LMNAMEN1
SCHEMBL9511803 0.87 MAPT (0.59) MAPTALDH1A1L3MBTL1GAALMNA
SCHEMBL308358 0.83 ALDH1A1 (0.71) MAPTALDH1A1L3MBTL1LMNAMEN1
SCHEMBL29112576 0.81 ALDH1A1 (0.63) MAPTALDH1A1L3MBTL1LMNAMEN1
SCHEMBL29860517 0.81 ALDH1A1 (0.63) MAPTALDH1A1L3MBTL1LMNAMEN1
SCHEMBL6142361 0.80 MAPT (0.51) MAPTALDH1A1L3MBTL1GAALMNA
SCHEMBL9511849 0.79 ADORA2A (0.61) MAPTALDH1A1L3MBTL1GAALMNA
SCHEMBL28923230 0.77 MAPT (0.55) MAPTALDH1A1L3MBTL1LMNAMEN1
SCHEMBL11841472 0.77 ADORA2A (0.50) MAPTALDH1A1L3MBTL1GAALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9268168-A None JP disclosed
JP-H09268168-A PRODUCTION OF 1-AMINO-5-BENZOYLAMINOANTHRAQUINONE MITSUI TOATSU CHEM INC 1997-10-14 JP disclosed
US-4231918-A THIOINDIGO OR DIOXAZINE PIGMENT AND DYE CIBA-GEIGY CORPORATION (US) 1980-11-04 US disclosed
US-4202815-A Concentrated powder or granular formulations dispersable in aqueous media ROHNER AG PRATTELN (CH) 1980-05-13 US disclosed
US-4179450-A Process for the preparation of 1-acylamino-5(8)-chloroanthraquinones BAYER AKTIENGESELLSCHAFT (DE) 1979-12-18 US disclosed
US-4141881-A PERYLENE-3,4,9,10-TETRACARBOXYLIC PIGMENT MIXTURE WITH DYE CIBA-GEIGY CORPORATION (US) 1979-02-27 US disclosed
US-4076736-A Preparation of aminoanthraquinones from nitroanthraquinones BAYER AKTIENGESELLSCHAFT (DT) 1978-02-28 US disclosed
US-3969302-A Process for the dyeing of colored shaped articles of high polymer, synthetic resins and preparations for such process CIBA-GEIGY AG (CH) 1976-07-13 US disclosed
US-3948828-A COLORING POLYESTERS OR POLYAMIDES CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed