Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | TACR1 | P25103 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27399357 | 0.80 | TEAD1 (0.34) | — | |
| SCHEMBL27399360 | 0.80 | TEAD1 (0.34) | — | |
| SCHEMBL27401285 | 0.77 | RORC (0.43) | LIPERORCGPR119TACR1 | |
| SCHEMBL30835927 | 0.77 | RORC (0.43) | LIPERORCGPR119TACR1 | |
| SCHEMBL21381806 | 0.74 | MAPT (0.47) | USP30RORCGPR119TACR1 | |
| SCHEMBL30836040 | 0.74 | MAPT (0.47) | USP30RORCGPR119TACR1 | |
| SCHEMBL27401990 | 0.72 | HDAC4 (0.38) | USP30RORCGPR119NR1H2AKT1 | |
| SCHEMBL31556570 | 0.72 | HDAC4 (0.38) | USP30RORCGPR119NR1H2AKT1 | |
| SCHEMBL27401519 | 0.70 | MAOB (0.48) | RORCGPR119TACR1 | |
| SCHEMBL28687516 | 0.70 | NR1H2 (0.47) | USP30RORCNR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| CN-119894866-A | YAP/TAZ-TEAD oncoprotein inhibitors | 布里奇恩生物科学公司 | 2025-04-25 | — | — | CN | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |