Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 1/20 | 0.43 |
| ▸ | LIPE | Q05469 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.39 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27401285 | 1.00 | RORC (0.43) | RORCLIPEMAPTGPR119HPGD | |
| SCHEMBL30836040 | 0.83 | MAPT (0.47) | RORCMAPTGPR119TACR1 | |
| SCHEMBL21381806 | 0.83 | MAPT (0.47) | RORCMAPTGPR119TACR1 | |
| SCHEMBL27401246 | 0.80 | TEAD1 (0.42) | HPGDSMN1; SMN2HRH3 | |
| SCHEMBL30835888 | 0.80 | TEAD1 (0.42) | HPGDSMN1; SMN2HRH3 | |
| SCHEMBL31664271 | 0.79 | SLC6A9 (0.48) | RORCLIPEMAPTGPR119HPGD | |
| SCHEMBL22462815 | 0.79 | RORC (0.43) | RORCMAPTGPR119TACR1ENPP2 | |
| SCHEMBL29511830 | 0.79 | RORC (0.43) | RORCMAPTGPR119TACR1ENPP2 | |
| SCHEMBL21723087 | 0.78 | RORC (0.42) | RORCMAPTGPR119TACR1ENPP2 | |
| SCHEMBL30835965 | 0.77 | USP30 (0.37) | RORCLIPEGPR119TACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4587424-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | Bridgene Biosciences, Inc. (US) | 2025-07-23 | — | — | EP | disclosed |
| WO-2024059317-A1 | YAP/TAZ-TEAD ONCOPROTEINS INHIBITORS | BRIDGENE BIOSCIENCES, INC. (US) | 2024-03-21 | — | — | WO | disclosed |