Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | HRH1 | P35367 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GBA1 | P04062 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 2/20 | 0.34 |
| ▸ | KIF11 | P52732 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174463 | 0.93 | HRH1 (0.50) | CYP2D6HRH1MEN1KMT2ALMNA | |
| SCHEMBL10794455 | 0.74 | MAOB (0.43) | CYP2D6HRH1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL7650165 | 0.73 | KIF11 (0.38) | CYP2D6HRH1MEN1KMT2ALMNA | |
| Hydrochloric Acid SCHEMBL10798935 | 0.72 | MAOB (0.42) | CYP2D6HRH1MEN1KMT2ALMNA | |
| SCHEMBL29441284 | 0.70 | KIF11 (0.52) | MEN1KMT2ANPC1RAB9AKIF11 | |
| SCHEMBL29174447 | 0.69 | CHRM3 (0.44) | CYP2D6HRH1MEN1KMT2AMAPK1 | |
| SCHEMBL30836892 | 0.68 | SLC6A1 (0.41) | CYP2D6HRH1CYP1A2 | |
| SCHEMBL11606097 | 0.66 | HRH1 (0.61) | CYP2D6HRH1MEN1KMT2ALMNA | |
| SCHEMBL29174493 | 0.66 | KIF11 (0.42) | CYP2D6LMNACYP1A2CYP2C19HTR2C | |
| SCHEMBL29174475 | 0.66 | KDM1A (0.41) | CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324715-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117750962-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-03-22 | — | — | CN | disclosed |