Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A1 | P30531 | 1/20 | 0.41 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.38 |
| ▸ | DRD5 | P21918 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.36 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29174467 | 0.94 | CHRNA7 (0.42) | SLC6A1SLC6A11DRD2DRD3CHRNA7 | |
| SCHEMBL29174459 | 0.82 | DRD2 (0.54) | DRD2DRD1DRD4DRD5DRD3 | |
| SCHEMBL30836802 | 0.78 | CCR1 (0.43) | CHRM2CHRM1CHRM3 | |
| SCHEMBL29174447 | 0.77 | CHRM3 (0.44) | DRD1DRD3CYP2D6CHRM2CHRM1 | |
| SCHEMBL27225550 | 0.75 | CYP3A4 (0.34) | SLC6A1SLC6A11CYP3A4CYP2D6 | |
| SCHEMBL30836860 | 0.73 | SIGMAR1 (0.41) | SLC6A1SLC6A11CYP3A4CARM1PRMT6 | |
| SCHEMBL29174475 | 0.73 | KDM1A (0.41) | CYP2D6CHRM3KCNH2 | |
| SCHEMBL29174461 | 0.71 | GPR119 (0.54) | — | |
| SCHEMBL29174469 | 0.71 | ATM (0.45) | SLC6A1SLC6A11CYP3A4CYP1A2CYP2D6 | |
| SCHEMBL9912191 | 0.69 | DRD2 (0.65) | DRD2DRD1DRD4DRD5DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118324715-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-07-12 | — | — | CN | disclosed |
| CN-117750962-A | Compounds, compositions, and methods of use thereof | 艾勒维生技公司 | 2024-03-22 | — | — | CN | disclosed |