Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.47 |
| ▸ | ADRB3 | P13945 | 3/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29181095 | 1.00 | ADRB2 (0.47) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL30837392 | 0.86 | IP6K1 (0.46) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL29181045 | 0.86 | IP6K1 (0.46) | MAPTHTTMEN1KMT2AALDH1A1 | |
| SCHEMBL30837358 | 0.82 | SIRT6 (0.50) | SIRT6MAPTHTTMEN1KMT2A | |
| SCHEMBL29181041 | 0.82 | SIRT6 (0.50) | SIRT6MAPTHTTMEN1KMT2A | |
| SCHEMBL29181017 | 0.81 | HTR6 (0.47) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL30837311 | 0.81 | HTR6 (0.47) | ADRB2ADRB1ADRB3ADRA1DADRA1A | |
| SCHEMBL29138185 | 0.80 | SIRT6 (0.66) | SIRT6MAPTMEN1KMT2AHTR6 | |
| SCHEMBL30837330 | 0.80 | SIRT6 (0.47) | SIRT6MAPTHTTMEN1KMT2A | |
| SCHEMBL29181075 | 0.80 | SIRT6 (0.47) | SIRT6MAPTHTTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756703-B | Naphthalimide-based coronavirus papain-like protease inhibitors | 广州国家实验室 | 2024-12-10 | — | — | CN | disclosed |
| CN-117756703-A | Naphthalimide-based coronavirus papain-like protease inhibitors | 广州国家实验室 | 2024-03-26 | — | — | CN | disclosed |