Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCF1 | P14598 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2B | P41595 | 3/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | PLK4 | O00444 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.39 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.39 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28849227 | 0.83 | NPC1 (0.45) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31016542 | 0.81 | USP5 (0.47) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL6202367 | 0.78 | ALDH1A1 (0.42) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30838566 | 0.77 | LMNA (0.44) | ALDH1A1CYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL30838561 | 0.75 | PTGER4 (0.51) | ALDH1A1CYP2C9SSTR4HDAC3HDAC1 | |
| SCHEMBL19272107 | 0.74 | NCF1 (0.47) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL14431011 | 0.74 | NCF1 (0.47) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL264120 | 0.74 | NCF1 (0.52) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL13868218 | 0.74 | NCF1 (0.52) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL1496311 | 0.74 | NCF1 (0.47) | NCF1ALDH1A1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071629-A1 | NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF | (주)제이디바이오사이언스 | 2024-04-04 | — | — | WO | disclosed |