Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 2/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29237320 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL30217397 | 0.80 | ALDH1A1 (0.43) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL21380032 | 0.80 | CES2 (0.56) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL28446997 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL30864811 | 0.80 | CES2 (0.56) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL27903880 | 0.80 | ALDH1A1 (0.53) | ALDH1A1GAACTSDCES2CES1 | |
| SCHEMBL1822227 | 0.79 | GAA (0.49) | ALDH1A1GAAHIF1ACES2CES1 | |
| SCHEMBL27711080 | 0.79 | HIF1A (0.49) | ALDH1A1GAAHIF1ACES2CES1 | |
| SCHEMBL15695564 | 0.77 | HIF1A (0.48) | ALDH1A1GAAHIF1ACES2CES1 | |
| SCHEMBL824969 | 0.77 | HIF1A (0.50) | GAAHIF1ACES2CES1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024071629-A1 | NOVEL FLUORENE DERIVATIVE COMPOUND AND USE THEREOF | (주)제이디바이오사이언스 | 2024-04-04 | — | — | WO | disclosed |