SCHEMBL824969

SCHEMBL824969

CC(C(=O)O)c1ccccc1F

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 3/20 0.50
PTGS2 P35354 10/20 0.49
PTGS1 P23219 9/20 0.49
MEN1 O00255 2/20 0.49
KMT2A Q03164 2/20 0.49
LMNA P02545 2/20 0.49
FABP2 P12104 1/20 0.49
TSHR P16473 1/20 0.49
AKR1C4 P17516 1/20 0.49
ADRA2B P18089 1/20 0.49
CHRM3 P20309 1/20 0.49
HTR2C P28335 1/20 0.49
DRD3 P35462 1/20 0.49
AKR1C3 P42330 1/20 0.49
AKR1C2 P52895 1/20 0.49
AKR1C1 Q04828 1/20 0.49
SLC22A6 Q4U2R8 1/20 0.49
CYP1A2 P05177 1/20 0.49
MAPT P10636 1/20 0.49
CYP2C9 P11712 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31117047 1.00 HIF1A (0.50) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL8142507 1.00 HIF1A (0.50) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL31415015 1.00 HIF1A (0.50) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL8142511 1.00 HIF1A (0.50) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL12800395 0.88 HIF1A (0.48) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL15695564 0.88 HIF1A (0.48) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL6491103 0.86 CES2 (0.51) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL27711080 0.85 HIF1A (0.49) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL11153495 0.85 PTGS2 (0.49) HIF1APTGS2PTGS1MEN1KMT2A
SCHEMBL2204495 0.84 PTGS2 (0.56) HIF1APTGS2PTGS1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 122 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108456140-B Method for preparing flurbiprofen impurity M 心邀(深圳)生物科技有限公司 2021-06-11 CN claimed
EP-2799424-B1 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE LTT BIO PHARMA CO LTD (JP) 2016-08-17 EP claimed
US-9221786-B2 2-fluorophenyl propionic acid derivatives LTT BIO-PHARMA CO., LTD. (JP) 2015-12-29 US claimed
US-20140330026-A1 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES LTT BIO-PHARMA CO., LTD. (JP) 2014-11-06 US claimed
EP-2799424-A1 2-FLUOROPHENYLPROPIONIC ACID DERIVATIVE LTT Bio-Pharma Co., Ltd. (JP) 2014-11-05 EP claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
US-4411974-A FOR NEGATIVE TONERS XEROX CORPORATION (US) 1983-10-25 US claimed
US-4367176-A Esters of arylpropionic acids endowed with an anti-inflammatory activity and related pharmaceutical compositions AUSONIA FARMACEUTICI S.R.L. (IT) 1983-01-04 US claimed
JP-57009757-A None JP disclosed
JP-8253440-A None JP disclosed
US-12605351-B2 Method for producing a composition comprising a 3-O-p-coumaroyl ester of tormentic acid from a plant cell culture, applications thereof as antiparasitic agent for the treatment of trypanosomiasis LUXEMBOURG INSTITUTE OF SCIENCE AND TECHNOLOGY (LU) 2026-04-21 US disclosed
EP-4682141-A1 TRICYCLIC COMPOUND ONO Pharmaceutical Co., Ltd. (JP) 2026-01-21 EP disclosed
WO-2025074305-A1 N-(1-(AMINOMETHYL)CYCLOPROPYL)(ARYL OR HETEROARYL) CARBOXAMIDE DERIVATIVES TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2025-04-10 WO disclosed
CN-119639276-A Ink composition, semiconductor nanoparticle-polymer composite prepared therefrom, electronic device, and display device 三星电子株式会社 2025-03-18 CN disclosed
JP-H08253440-A PREPARATION OF ENANTIOMER OF 2-(2-FLUORO-4BIPHENYL) PROPIONIC ACID ZAMBON GROUP SPA 1996-10-01 JP disclosed
EP-0712387-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS PHARMACIA & UPJOHN COMPANY (US) 1996-05-22 EP disclosed
WO-1995004713-A1 2-AMINOINDANS AS SELECTIVE DOPAMINE D3 LIGANDS THE UPJOHN COMPANY (US) 1995-02-16 WO disclosed
US-4411974-A FOR NEGATIVE TONERS XEROX CORPORATION (US) 1983-10-25 US disclosed
JP-S579757-A ALPHA-SULFONYL 2-FLUORO-4-BIPHENYLYL ACETIC ACID DERIVATIVE SAGAMI CHEM RES CENTER 1982-01-19 JP disclosed
US-4008270-A Process for preparing 2-(substituted phenyl)propionic acids THE UPJOHN COMPANY (US) 1977-02-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12605351-B2 Method for producing a composition comprising a 3-O-p-coumaroyl ester of tormentic acid from a plant cell culture, applications thereof as antiparasitic agent for the treatment of trypanosomiasis NFATC1, CYP51A1, ME1 HIF1A 1661/4885PTGS2 1657/4885PTGS1 1096/4885
US-20140330026-A1 2-FLUOROPHENYL PROPIONIC ACID DERIVATIVES FPR1, OPRK1, FPR2 HIF1A 395/4885PTGS2 127/4885PTGS1 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.