Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 2/20 | 0.37 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | CYP51A1 | Q16850 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 5/20 | 0.35 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | NR3C1 | P04150 | 3/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24252081 | 0.84 | SOAT1 (0.35) | CNR2KCNN4LMNAHSP90AA1CYP3A4 | |
| SCHEMBL28746008 | 0.82 | PRKAB2 (0.40) | CNR1CNR2KCNN4LMNAHSP90AA1 | |
| SCHEMBL24836099 | 0.81 | CNR2 (0.42) | CNR1CNR2 | |
| SCHEMBL18649480 | 0.80 | RIPK1 (0.39) | KCNN4LMNAHSP90AA1CYP3A4CYP19A1 | |
| SCHEMBL25458297 | 0.77 | KCNN4 (0.37) | KCNN4LMNAHSP90AA1CYP3A4CYP19A1 | |
| SCHEMBL30838760 | 0.77 | KCNN4 (0.44) | KCNN4CYP3A4CYP2C9HDAC6HDAC3 | |
| SCHEMBL17552743 | 0.76 | RIPK1 (0.41) | KCNN4LMNAHSP90AA1CYP3A4CYP19A1 | |
| SCHEMBL24756685 | 0.74 | KCNN4 (0.37) | KCNN4LMNAHSP90AA1CYP3A4CYP19A1 | |
| SCHEMBL19925403 | 0.74 | KCNN4 (0.40) | KCNN4LMNAHSP90AA1CYP3A4CYP19A1 | |
| SCHEMBL19589711 | 0.73 | NFE2L2 (0.38) | CNR1CNR2KCNN4LMNAHSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114591272-B | Preparation method of intermediate compound used for synthesizing posaconazole and intermediate compound prepared by same | 浙江奥翔药业股份有限公司 | 2024-04-05 | — | — | CN | disclosed |