Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Phosphoric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 10/20 | 0.35 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Abeprazan SCHEMBL29201774 | 0.82 | HTR6 (0.37) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL23658928 | 0.80 | HTR6 (0.42) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL30963571 | 0.79 | MEN1 (0.42) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL31512541 | 0.79 | HTR6 (0.39) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL19385605 | 0.79 | MEN1 (0.42) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL30963578 | 0.79 | MEN1 (0.40) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL19385625 | 0.79 | MEN1 (0.40) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL29201835 | 0.78 | HTR6 (0.34) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL28566174 | 0.78 | HTR6 (0.41) | KMT2AMEN1GFERHTR6DRD2 | |
| SCHEMBL23677771 | 0.78 | MEN1 (0.39) | KMT2AMEN1GFERHTR6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756694-A | High water soluble salt of new 4-methoxy pyrrole derivative and its preparation method | 罗欣药业(上海)有限公司 | 2024-03-26 | — | — | CN | claimed |