Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR3 | P49019 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | RXRA | P19793 | 1/20 | 0.38 |
| ▸ | RXRB | P28702 | 1/20 | 0.38 |
| ▸ | RXRG | P48443 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175771 | 1.00 | HCAR3 (0.47) | HCAR3KDM4ENPC1L3MBTL1ALDH1A1 | |
| SCHEMBL794476 | 0.84 | HCAR3 (0.47) | HCAR3ALDH1A1MAPTLMNARXRA | |
| SCHEMBL794446 | 0.81 | HCAR3 (0.44) | HCAR3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL806435 | 0.80 | USP2 (0.49) | HCAR3NPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL30839258 | 0.80 | L3MBTL1 (0.44) | HCAR3NPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL29175741 | 0.80 | L3MBTL1 (0.44) | HCAR3NPC1L3MBTL1ALDH1A1MAPT | |
| SCHEMBL794057 | 0.78 | HCAR3 (0.42) | HCAR3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL21929417 | 0.76 | HCAR3 (0.40) | HCAR3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL30854893 | 0.76 | HCAR3 (0.40) | HCAR3ALDH1A1MAPTLMNAPOLB | |
| SCHEMBL793888 | 0.76 | HCAR3 (0.40) | HCAR3ALDH1A1MAPTLMNARET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756805-A | Pteridinone derivatives as RSK inhibitors and their use | 华东师范大学 | 2024-03-26 | — | — | CN | disclosed |