Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HCAR3 | P49019 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29175741 | 1.00 | L3MBTL1 (0.44) | L3MBTL1ALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL30839246 | 0.80 | HCAR3 (0.47) | L3MBTL1ALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL794476 | 0.80 | HCAR3 (0.47) | ALDH1A1MAPTHCAR3SMN1; SMN2HPGD | |
| SCHEMBL29175771 | 0.80 | HCAR3 (0.47) | L3MBTL1ALDH1A1MAPTHCAR3RAB9A | |
| SCHEMBL5413224 | 0.78 | RXRA (0.54) | ALDH1A1MAPTRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL21198132 | 0.77 | CYP1A2 (0.44) | L3MBTL1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL794446 | 0.77 | HCAR3 (0.44) | ALDH1A1MAPTHCAR3POLBLMNA | |
| SCHEMBL16308649 | 0.76 | MAPT (0.40) | L3MBTL1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL5375050 | 0.76 | CYP1A2 (0.39) | L3MBTL1ALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL31482836 | 0.76 | CYP1A2 (0.39) | L3MBTL1ALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117756805-A | Pteridinone derivatives as RSK inhibitors and their use | 华东师范大学 | 2024-03-26 | — | — | CN | disclosed |