SCHEMBL30839484

SCHEMBL30839484

C[C@@H](O)[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)[C@@H](C)O)C(=O)O

nearest known ligand 0.64

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
OPRD1 P41143 10/20 0.64
OPRM1 P35372 8/20 0.64
SLC6A2 P23975 1/20 0.54
OPRK1 P41145 2/20 0.53
SLC7A5 Q01650 1/20 0.49
NPY1R P25929 1/20 0.48
NPY2R P49146 1/20 0.48
NPY4R P50391 1/20 0.48
YARS1 P54577 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30839485 1.00 OPRD1 (0.64) OPRD1OPRM1SLC6A2OPRK1SLC7A5
SCHEMBL30811089 0.96 OPRD1 (0.63) OPRD1OPRM1SLC6A2OPRK1
SCHEMBL31257017 0.95 SLC6A2 (0.59) OPRD1OPRM1SLC6A2OPRK1NPY1R
SCHEMBL29823718 0.94 OPRD1 (0.70) OPRD1OPRM1SLC6A2OPRK1
SCHEMBL30565312 0.92 OPRD1 (0.59) OPRD1OPRM1SLC6A2OPRK1
SCHEMBL29987086 0.92 OPRM1 (0.56) OPRD1OPRM1SLC6A2OPRK1NPY1R
SCHEMBL9822736 0.92 SLC7A5 (0.58) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL8529219 0.92 SLC7A5 (0.58) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL8529222 0.92 SLC7A5 (0.58) OPRD1OPRM1OPRK1SLC7A5YARS1
SCHEMBL30309232 0.92 SLC7A5 (0.58) OPRD1OPRM1OPRK1SLC7A5YARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240083949-A1 CELL PENETRATING PEPTIDE COMPOSITIONS AND METHODS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-03-14 US claimed
US-20240083949-A1 CELL PENETRATING PEPTIDE COMPOSITIONS AND METHODS THEREOF THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-03-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240083949-A1 CELL PENETRATING PEPTIDE COMPOSITIONS AND METHODS THEREOF VIP, IAPP, ANXA5 OPRD1 4341/4885OPRM1 4159/4885SLC6A2 2166/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.