SCHEMBL8529222

SCHEMBL8529222

C[C@@H](O)[C@H](NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)O

nearest known ligand 0.58

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 1/20 0.58
OPRD1 P41143 9/20 0.57
OPRM1 P35372 6/20 0.57
YARS1 P54577 2/20 0.55
MME P08473 1/20 0.53
OPRK1 P41145 1/20 0.51
ERAP2 Q6P179 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9822736 1.00 SLC7A5 (0.58) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL30309232 1.00 SLC7A5 (0.58) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL8529219 1.00 SLC7A5 (0.58) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL30520377 0.95 OPRD1 (0.55) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL30017206 0.92 OPRD1 (0.62) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL30839485 0.92 OPRD1 (0.64) SLC7A5OPRD1OPRM1YARS1OPRK1
SCHEMBL31193449 0.92 OPRD1 (0.52) SLC7A5OPRD1OPRM1YARS1MME
SCHEMBL30839484 0.92 OPRD1 (0.64) SLC7A5OPRD1OPRM1YARS1OPRK1
SCHEMBL29823718 0.91 OPRD1 (0.70) OPRD1OPRM1MMEOPRK1
SCHEMBL22872688 0.90 ERAP2 (0.52) SLC7A5OPRD1OPRM1YARS1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12097237-B2 Small molecule Ras inhibitors OHIO STATE INNOVATION FOUNDATION (US) 2024-09-24 US claimed
WO-2026107097-A1 SELF-IMMOLATIVE LINKERS AND CONJUGATES THEREOF ENLAZA THERAPEUTICS, INC. (US) 2026-05-21 WO disclosed
EP-4709750-A1 BISPECIFIC ANTI-PSEUDOMONAS ANTIBODIES WITH MODIFIED FC REGIONS AND METHODS OF USE THEREOF Astrazeneca AB (SE) 2026-03-18 EP disclosed
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS STEALTH BIOTHERAPEUTICS INC. (US) 2026-03-05 US disclosed
EP-4661891-A2 PEPTIDES FOR TREATING NEUROLOGICAL DISORDERS Creative Bio-Peptides Inc. (US) 2025-12-17 EP disclosed
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2025-08-21 US disclosed
US-20250236848-A1 DEVELOPMENT OF DENGUE VIRUS VACCINE COMPONENTS The Government of the USA as represented by the Secretary, Dept. of Health and Human Services (US) 2025-07-24 US disclosed
US-12297502-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2025-05-13 US disclosed
US-20250109167-A1 METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE STEALTH BIOTHERAPEUTICS INC. (US) 2025-04-03 US disclosed
US-12203100-B2 Development of dengue virus vaccine components The Government of the USA as represented by the Secretary, Dept. of Health and Human Services (US) 2025-01-21 US disclosed
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE STEALTH BIOTHERAPEUTICS INC. (US) 2022-09-08 US disclosed
US-20220251521-A1 DEVELOPMENT OF DENGUE VIRUS VACCINE COMPONENTS The Government of the USA as represented by the Secretary, Dept. of Health and Human Services (US) 2022-08-11 US disclosed
US-11332722-B2 Development of dengue virus vaccine components THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2022-05-17 US disclosed
US-11312993-B2 Methods and compositions for detecting and diagnosing diseases and conditions STEALTH BIOTHERAPEUTICS INC. (US) 2022-04-26 US disclosed
WO-2022068784-A1 SELENIUM-RICH CORDYCEPS MILITARIS DERIVED ACTIVE SELENIUM PEPTIDE WITH NEURON PROTECTION FUNCTION, AND PREPARATION METHOD THEREFOR AND USE THEREOF 暨南大学 2022-04-07 WO disclosed
CN-114164134-A Bifidobacterium longum subspecies longum with functions of preventing and relieving colitis symptoms and application thereof 东北农业大学 2022-03-11 CN disclosed
US-11266709-B2 Methods for the regulation of matrix metalloproteinase expression STEALTH BIOTHERAPEUTICS INC. (US) 2022-03-08 US disclosed
EP-0885899-A1 Method for obtaining peptide fragments by use of fluorinated organic acids SEIKO INSTRUMENTS INC. (JP) 1998-12-23 EP disclosed
US-5036052-A Containing a dipeptide of tryptophan and alanine or lecine and no stabilizer; discoloration inhibition MORISHITA PHARMACEUTICAL CO., LTD. (JP) 1991-07-30 US disclosed
EP-0347890-A1 Amino acid nutrient compositions Roussel Morishita Co., Ltd. (JP) 1989-12-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12097237-B2 Small molecule Ras inhibitors KRAS, HRAS, NRAS SLC7A5 2871/4885OPRD1 4285/4885OPRM1 4514/4885
US-20250109167-A1 METHODS FOR THE TREATMENT OF MITOCHONDRIAL DISEASE NLN, OAT, HAGH SLC7A5 1446/4885OPRD1 3823/4885OPRM1 3263/4885
US-20220280593-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 SLC7A5 414/4885OPRD1 1466/4885OPRM1 898/4885
US-20260062752-A1 METHODS AND COMPOSITIONS FOR DETECTING AND DIAGNOSING DISEASES AND CONDITIONS ARG2, MTPN, TNNT2 SLC7A5 1118/4885OPRD1 4441/4885OPRM1 4686/4885
US-20250262269-A1 METHODS FOR PERFORMING A CORONARY ARTERY BYPASS GRAFT PROCEDURE RNPEP, TNNI3, BDKRB1 SLC7A5 414/4885OPRD1 1466/4885OPRM1 898/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.