SCHEMBL30841998

SCHEMBL30841998

CS(=O)(=O)Nc1cc(CC(N)=O)ccc1O

nearest known ligand 0.62

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.62
ADRA2B P18089 2/20 0.62
ADRA2C P18825 2/20 0.62
ADRA1A P35348 2/20 0.62
ADRB3 P13945 17/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4303130 0.82 NPC1 (0.43) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL8632112 0.81 ADRA2A (0.69) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL3657859 0.81 ADRB3 (0.42) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL3633978 0.81 TRPV1 (0.51)
SCHEMBL9687730 0.80 ADRA2A (0.73) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL4535018 0.79 ADRB3 (0.46) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL7040773 0.78 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL13293368 0.78 ADRA2A (0.75) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL7242198 0.78 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL6707802 0.77 ADRA2A (0.43) ADRA2AADRA2BADRA2CADRA1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024067560-A1 SULFONAMIDE COMPOUND AND MEDICAL USE THEREOF 中国药科大学 2024-04-04 WO disclosed