SCHEMBL8632112

SCHEMBL8632112

CS(=O)(=O)Nc1cc(CO)ccc1O

nearest known ligand 0.69

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ADRA2A P08913 2/20 0.69
ADRA2B P18089 2/20 0.69
ADRA2C P18825 2/20 0.69
ADRA1A P35348 2/20 0.69
ADRB3 P13945 16/20 0.54
EP300 Q09472 1/20 0.47
KAT2B Q92831 1/20 0.47
KAT8 Q9H7Z6 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7040773 0.83 ADRA2A (0.66) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL13293368 0.83 ADRA2A (0.75) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL9687730 0.82 ADRA2A (0.73) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL30841998 0.81 ADRA2A (0.62) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL7242198 0.80 ADRA2A (0.61) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL18088741 0.79 ADRA2A (0.45) ADRA2AADRA2BADRA2CADRA1A
SCHEMBL7723614 0.78 ADRA2A (0.58) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL5761857 0.78 PTGES2 (0.45) ADRA2AADRA2BADRA2CADRA1A
Hydrochloric Acid SCHEMBL11670739 0.77 ADRA2B (0.70) ADRA2AADRA2BADRA2CADRA1AADRB3
SCHEMBL7674723 0.77 KDM6B (0.59) ADRA2AADRA2BADRA2CADRA1AADRB3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0547707-B1 Blocked photographically useful compounds for use with peroxide-containing processes EASTMAN KODAK CO (US) 1998-07-01 EP disclosed
US-5538834-A Blocked photographically useful compounds for use with peroxide-containing processes EASTMAN KODAK COMPANY (US) 1996-07-23 US disclosed
EP-0547707-A1 Blocked photographically useful compounds for use with peroxide-containing processes EASTMAN KODAK COMPANY (US) 1993-06-23 EP disclosed