SCHEMBL30842166

SCHEMBL30842166

CSCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CC(C)C)C(=O)NC(C)(C)C(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ TFPI P10646 7/20 0.57
▸ KDM1A O60341 3/20 0.56
▸ GLP1R P43220 1/20 0.55
▸ OPRM1 P35372 2/20 0.55
▸ OPRD1 P41143 2/20 0.55
▸ OPRK1 P41145 2/20 0.55
▸ EPHA2 P29317 2/20 0.55
▸ NMUR2 Q9GZQ4 1/20 0.55
▸ NMUR1 Q9HB89 1/20 0.55
▸ MAOB P27338 1/20 0.54
▸ KDM5A P29375 1/20 0.54
▸ KDM1B Q8NB78 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30842159 0.93 NMUR2 (0.64) TFPIOPRM1OPRD1EPHA2NMUR2
SCHEMBL30842169 0.90 NMUR2 (0.65) TFPIOPRM1OPRD1NMUR2NMUR1
SCHEMBL30176214 0.89 KDM1A (0.60) TFPIKDM1ANMUR2NMUR1MAOB
SCHEMBL29477190 0.87 TFPI (0.61) TFPIKDM1AOPRM1OPRK1NMUR2
SCHEMBL31415954 0.87 KDM1A (0.56) KDM1AOPRM1OPRK1MAOBKDM5A
SCHEMBL16976076 0.87 KDM1A (0.62) TFPIKDM1AOPRM1OPRK1EPHA2
SCHEMBL30842156 0.87 NMUR2 (0.65) TFPIOPRM1OPRD1NMUR2NMUR1
SCHEMBL30842174 0.86 MC4R (0.58) TFPIOPRM1OPRD1EPHA2NMUR2
SCHEMBL30842181 0.86 NMUR2 (0.64) TFPIOPRM1OPRD1EPHA2NMUR2
SCHEMBL30359272 0.86 OPRM1 (0.62) TFPIKDM1AOPRM1OPRK1NMUR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US claimed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US claimed
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US disclosed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US disclosed
US-11911464-B2 Anti-parasitic immunological compositions PROMMUNE, INC. (US) 2024-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides C5AR1, C5AR2, C3AR1 TFPI 1772/4885KDM1A 1521/4885GLP1R 635/4885
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS C3AR1, C5AR1, C5AR2 TFPI 895/4885KDM1A 2838/4885GLP1R 1960/4885
US-11911464-B2 Anti-parasitic immunological compositions C3AR1, C5AR1, C5AR2 TFPI 895/4885KDM1A 2838/4885GLP1R 1960/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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