SCHEMBL30842174

SCHEMBL30842174

CSCC[C@H](NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CCCCN)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CO)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N1CCC[C@H]1C(=O)NCC(=O)N[C@@H](CCCNC(=N)N)C(=O)O

nearest known ligand 0.67

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 1/20 0.58
▸ MC5R P33032 1/20 0.58
▸ MC3R P41968 1/20 0.58
▸ MC1R Q01726 1/20 0.58
▸ NMUR2 Q9GZQ4 3/20 0.57
▸ NMUR1 Q9HB89 3/20 0.57
▸ OPRM1 P35372 1/20 0.57
▸ OPRD1 P41143 1/20 0.57
▸ NPY2R P49146 7/20 0.57
▸ NPY4R P50391 7/20 0.57
▸ NPY5R Q15761 7/20 0.57
▸ NPY1R P25929 5/20 0.57
▸ TFPI P10646 4/20 0.57
▸ CXCR4 P61073 2/20 0.56
▸ EPHA2 P29317 1/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30842159 0.92 NMUR2 (0.64) MC4RMC5RMC3RMC1RNMUR2
SCHEMBL29489270 0.91 TFPI (0.58) MC4RMC5RMC3RMC1RNMUR2
SCHEMBL29410232 0.89 KEAP1 (0.67) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL30842169 0.89 NMUR2 (0.65) MC4RMC5RMC3RMC1RNMUR2
SCHEMBL29489266 0.89 TFPI (0.64) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL30495837 0.89 OPRM1 (0.61) MC4RMC5RMC3RMC1RNMUR2
SCHEMBL30176214 0.88 KDM1A (0.60) NMUR2NMUR1NPY2RNPY4RNPY5R
SCHEMBL29854575 0.87 NPY2R (0.58) NPY2RNPY4RNPY5RNPY1RTFPI
SCHEMBL29477190 0.87 TFPI (0.61) NMUR2NMUR1OPRM1TFPI
SCHEMBL30842195 0.86 TFPI (0.65) OPRM1OPRD1TFPI

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US claimed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US claimed
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) 2026-02-17 — — US disclosed
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA 2024-07-18 — — US disclosed
US-11911464-B2 Anti-parasitic immunological compositions PROMMUNE, INC. (US) 2024-02-27 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12552848-B2 Hydrochloride salts of C5a receptor agonist peptides C5AR1, C5AR2, C3AR1 MC4R 62/4885MC5R 105/4885MC3R 113/4885
US-20240238414-A1 ANTI-PARASITIC IMMUNOLOGICAL COMPOSITIONS C3AR1, C5AR1, C5AR2 MC4R 2160/4885MC5R 2264/4885MC3R 2303/4885
US-11911464-B2 Anti-parasitic immunological compositions C3AR1, C5AR1, C5AR2 MC4R 2160/4885MC5R 2264/4885MC3R 2303/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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