Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRA | P25101 | 14/20 | 0.68 |
| ▸ | EDNRB | P24530 | 13/20 | 0.68 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7850015 | 0.84 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL9065130 | 0.84 | EDNRA (0.69) | EDNRAEDNRB | |
| SCHEMBL9063022 | 0.83 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL7224859 | 0.83 | EDNRB (0.68) | EDNRAEDNRB | |
| SCHEMBL8479988 | 0.82 | EDNRA (0.55) | EDNRAEDNRBATMSLC40A1NPSR1 | |
| SCHEMBL9064490 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL7232444 | 0.81 | EDNRA (1.00) | EDNRAEDNRB | |
| SCHEMBL8476607 | 0.78 | EDNRA (0.53) | EDNRAEDNRB | |
| SCHEMBL8481520 | 0.77 | EDNRA (0.50) | EDNRAEDNRBNPSR1 | |
| SCHEMBL8479643 | 0.75 | TSHR (0.46) | EDNRAEDNRBATMSLC40A1NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117836294-A | Biological antagonist containing aromatic ring, preparation method and application thereof | 上海翰森生物医药科技有限公司 | 2024-04-05 | — | — | CN | disclosed |