SCHEMBL30844637

SCHEMBL30844637

CCCOCC[C@H](N)C(=O)OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
SLC1A1 P43005 2/20 0.46
MAPK1 P28482 2/20 0.46
TDP1 Q9NUW8 2/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
CYP3A4 P08684 1/20 0.46
TSHR P16473 1/20 0.46
LMNA P02545 2/20 0.46
SMN1; SMN2 Q16637 1/20 0.46
SLC1A3 P43003 1/20 0.45
MAPT P10636 1/20 0.44
IDO1 P14902 1/20 0.43
LTA4H P09960 2/20 0.42
SLC6A2 P23975 1/20 0.41
SLC6A3 Q01959 1/20 0.41
KMT2A Q03164 1/20 0.41
SLC15A1 P46059 2/20 0.41
LAP3 P28838 1/20 0.41
CTSK P43235 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23811126 0.89 ALDH1A1 (0.46) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL23811170 0.89 ALDH1A1 (0.46) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL10678429 0.88 SLC1A1 (0.54) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL24205786 0.87 MAPT (0.48) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL23810968 0.87 MAPT (0.48) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL24205766 0.87 MAPT (0.48) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL12869905 0.86 ALDH1A1 (0.53) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
SCHEMBL3096935 0.86 ALDH1A1 (0.53) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
Hydrochloric Acid SCHEMBL9437522 0.85 ALDH1A1 (0.51) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1
Hydrochloric Acid SCHEMBL27876344 0.85 ALDH1A1 (0.51) ALDH1A1SLC1A1MAPK1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-08-21 US disclosed
EP-3878836-B1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD CHUGAI PHARMACEUTICAL CO LTD (JP) 2025-07-23 EP disclosed
US-12312297-B2 O-substituted serine derivative production method CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) 2025-05-27 US disclosed
CN-112969683-B Process for the preparation of O-substituted serine derivatives 中外制药株式会社 2024-05-14 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263365-A1 O-SUBSTITUTED SERINE DERIVATIVE PRODUCTION METHOD STS, SMOX, TST ALDH1A1 616/4885SLC1A1 1422/4885MAPK1 1834/4885
US-12312297-B2 O-substituted serine derivative production method STS, SMOX, TST ALDH1A1 616/4885SLC1A1 1422/4885MAPK1 1834/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.