Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.54 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.47 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.44 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 6/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | RAF1 | P04049 | 1/20 | 0.38 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.38 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.38 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Emidurdar SCHEMBL1463101 | 1.00 | KCNMA1 (0.54) | KCNMA1GRIK1TMPRSS4GPR35TRPV1 | |
| SCHEMBL4718263 | 0.92 | GPR35 (0.47) | KCNMA1GRIK1GPR35TRPV1MAPT | |
| SCHEMBL1462393 | 0.91 | GRIK1 (0.60) | KCNMA1GRIK1GPR35TRPV1MAPT | |
| SCHEMBL2834395 | 0.88 | KCNMA1 (0.69) | KCNMA1TMPRSS4GPR35MAPTKDR | |
| SCHEMBL1463472 | 0.87 | GRIK1 (0.47) | KCNMA1GRIK1TMPRSS4TRPV1MAPT | |
| SCHEMBL3579491 | 0.86 | PSEN1 (0.47) | KCNMA1TRPV1MAPTKDRCA12 | |
| SCHEMBL1463507 | 0.85 | KMT2A (0.45) | GRIK1MAPTCA12CA1CA2 | |
| SCHEMBL3580763 | 0.85 | PSEN1 (0.45) | KCNMA1GRIK1TMPRSS4TRPV1MAPT | |
| SCHEMBL1463403 | 0.84 | KDR (0.45) | GRIK1MAPTKDRCA12CA1 | |
| SCHEMBL3574142 | 0.84 | PSEN1 (0.44) | KCNMA1GRIK1TMPRSS4TRPV1KDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117916224-A | Thermodynamically stable form of SCO-101 | 思坎迪昂肿瘤学股份有限公司 | 2024-04-19 | — | — | CN | disclosed |