Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 3/20 | 0.53 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | PRCP | P42785 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16105052 | 0.96 | FKBP1A (0.50) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL28901006 | 0.85 | PREP (0.53) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL2768429 | 0.85 | PREP (0.60) | PREPACE2RAB9ATSHRSMN1; SMN2 | |
| SCHEMBL6351728 | 0.83 | RAB9A (0.49) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL1388075 | 0.82 | PREP (0.55) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL6597133 | 0.82 | PREP (0.52) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL1873488 | 0.82 | PREP (0.52) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL7939228 | 0.82 | PREP (0.52) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL27987768 | 0.81 | GFER (0.48) | PREPACE2RAB9ATSHRCYP3A4 | |
| SCHEMBL11560321 | 0.81 | FKBP1A (0.57) | PREPACE2RAB9ASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114957182-B | USP8 inhibitor containing flavone skeleton structure and application thereof | 中国药科大学 | 2024-03-15 | — | — | CN | disclosed |