Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 8/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12696551 | 1.00 | GAA (0.43) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL30213788 | 0.83 | GAA (0.44) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL12384855 | 0.83 | GAA (0.44) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL26326228 | 0.82 | GAA (0.43) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL25475022 | 0.81 | GAA (0.42) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL18538833 | 0.81 | GAA (0.42) | GAALMNAKMT2AHTR7POLB | |
| SCHEMBL12032333 | 0.80 | PIN1 (0.37) | PIN1LMNAKMT2APOLBALDH1A1 | |
| SCHEMBL29206027 | 0.79 | LMNA (0.37) | PIN1LMNAKMT2AKDM4EPOLB | |
| SCHEMBL17963746 | 0.79 | HTR7 (0.46) | GAAPIN1LMNAKMT2AHTR7 | |
| SCHEMBL30846791 | 0.79 | LMNA (0.37) | PIN1LMNAKMT2AKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117843633-A | Sulfoximine compounds, pharmaceutical compositions and uses thereof | 上海海和药物研究开发股份有限公司 | 2024-04-09 | — | — | CN | disclosed |