Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 2/20 | 0.38 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GBA1 | P04062 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27112718 | 1.00 | ROCK2 (0.39) | ROCK2PIM1PIM2LMNAGBA1 | |
| SCHEMBL18202586 | 0.93 | ADRB2 (0.38) | ROCK2PIM1PIM2LMNAGBA1 | |
| SCHEMBL30608169 | 0.92 | PIM1 (0.46) | ROCK2PIM1PIM2LMNAGBA1 | |
| SCHEMBL23494625 | 0.92 | PIM1 (0.46) | ROCK2PIM1PIM2LMNAGBA1 | |
| SCHEMBL21478688 | 0.92 | PIM1 (0.46) | ROCK2PIM1PIM2LMNAGBA1 | |
| SCHEMBL21478409 | 0.89 | EZH2 (0.36) | ROCK2PIM1PIM2KDM1AHDAC1 | |
| SCHEMBL30608173 | 0.89 | EZH2 (0.36) | ROCK2PIM1PIM2KDM1AHDAC1 | |
| SCHEMBL25217244 | 0.82 | PIM1 (0.38) | ROCK2PIM1PIM2CNR1GAA | |
| SCHEMBL24265615 | 0.79 | PIM1 (0.38) | PIM1PIM2LMNAGBA1CYP1A2 | |
| SCHEMBL28663871 | 0.77 | ROCK2 (0.51) | ROCK2PIM1PIM2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024044757-A1 | AMINOPYRIMIDINE AND AMINOTRIAZINE DERIVATIVES AS MYC PROTEIN MODULATORS | Sanford Burnham Prebys Medical Discovery Institute (US) | 2024-02-29 | — | — | WO | disclosed |