Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 11/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.32 |
| ▸ | POLQ | O75417 | 5/20 | 0.31 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847649 | 1.00 | CMA1 (0.35) | CMA1CRHR1POLQNTRK1MGAT2 | |
| SCHEMBL30847699 | 0.86 | TACR3 (0.34) | CMA1POLQNTRK1 | |
| SCHEMBL30847768 | 0.84 | POLQ (0.40) | CMA1CRHR1POLQ | |
| SCHEMBL30847728 | 0.83 | POLQ (0.42) | CMA1POLQMGAT2 | |
| SCHEMBL30847639 | 0.81 | POLQ (0.41) | CMA1CRHR1POLQ | |
| SCHEMBL29313853 | 0.80 | ALDH1A1 (0.31) | — | |
| SCHEMBL30847821 | 0.79 | POLQ (0.39) | CMA1CRHR1POLQ | |
| SCHEMBL30847731 | 0.78 | POLQ (0.38) | CMA1POLQ | |
| SCHEMBL30847750 | 0.77 | LIPE (0.34) | CMA1POLQ | |
| SCHEMBL30847696 | 0.77 | POLQ (0.36) | POLQMGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |