Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 5/20 | 0.36 |
| ▸ | DRD3 | P35462 | 5/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30847611 | 0.84 | DRD3 (0.40) | DRD2DRD3KCNH2HDAC1 | |
| SCHEMBL30847656 | 0.81 | DRD2 (0.34) | DRD2DRD3KCNH2 | |
| SCHEMBL30847729 | 0.76 | POLQ (0.38) | DRD2DRD3 | |
| SCHEMBL30847735 | 0.76 | POLQ (0.38) | DRD2DRD3 | |
| SCHEMBL30847803 | 0.76 | DRD2 (0.36) | DRD2DRD3KCNH2HDAC1 | |
| SCHEMBL30847604 | 0.76 | DRD2 (0.36) | DRD2DRD3KCNH2HDAC1 | |
| SCHEMBL30847670 | 0.76 | DRD2 (0.36) | DRD2DRD3KCNH2HDAC1 | |
| SCHEMBL30847580 | 0.69 | SCN5A (0.43) | — | |
| SCHEMBL30847593 | 0.69 | TACR1 (0.33) | — | |
| SCHEMBL30847592 | 0.67 | CMA1 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598901-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | Thomas Jefferson University (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024076964-A1 | PYRROLIDINE AND IMIDAZOLIDINE BASED DNA POLYMERASE THETA INHIBITORS AND USE THEREOF | THOMAS JEFFERSON UNIVERSITY (US) | 2024-04-11 | — | — | WO | disclosed |