Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.35 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.32 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.31 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.31 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.31 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29171913 | 1.00 | TSHR (0.39) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL30848412 | 0.86 | TTR (0.42) | ALDH1A1KMT2AL3MBTL1ABCC9ABCC8 | |
| SCHEMBL29172058 | 0.86 | TTR (0.42) | ALDH1A1KMT2AL3MBTL1ABCC9ABCC8 | |
| SCHEMBL30848332 | 0.82 | MAPT (0.34) | L3MBTL1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29172030 | 0.82 | NOTUM (0.41) | ALDH1A1MEN1KMT2AL3MBTL1CYP3A4 | |
| SCHEMBL29171886 | 0.76 | HTT (0.41) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL30848020 | 0.76 | HTT (0.41) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL29171893 | 0.76 | TTR (0.42) | TSHRAPOBEC3AHTTAPOBEC3GNCOA1 | |
| SCHEMBL29172009 | 0.74 | AR (0.34) | MEN1KMT2AL3MBTL1ADRB2 | |
| SCHEMBL30848145 | 0.74 | AR (0.34) | MEN1KMT2AL3MBTL1ADRB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |