Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | TPMT | P51580 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.34 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.34 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.34 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
| ▸ | RXRG | P48443 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172058 | 1.00 | TTR (0.42) | TTRTPMTALDH1A1HPGDABCC9 | |
| SCHEMBL30848234 | 0.86 | TSHR (0.39) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29171913 | 0.86 | TSHR (0.39) | ALDH1A1ABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL29172030 | 0.84 | NOTUM (0.41) | ALDH1A1XDHKMT2ALMNAL3MBTL1 | |
| SCHEMBL30848332 | 0.84 | MAPT (0.34) | HPGDABCC9ABCC8KCNJ11KCNJ8 | |
| SCHEMBL30848187 | 0.76 | TTR (0.46) | TTRTPMTALDH1A1HPGDKMT2A | |
| SCHEMBL29172009 | 0.76 | AR (0.34) | KMT2AL3MBTL1AR | |
| SCHEMBL30848145 | 0.76 | AR (0.34) | KMT2AL3MBTL1AR | |
| SCHEMBL29172054 | 0.76 | TTR (0.46) | TTRTPMTALDH1A1HPGDKMT2A | |
| SCHEMBL9478920 | 0.74 | TTR (0.56) | TTRTPMTALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |