Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | QPCT | Q16769 | 7/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | QPCTL | Q9NXS2 | 2/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29172092 | 1.00 | PDE10A (0.48) | PDE10APKMQPCTPOLBHPGD | |
| SCHEMBL28195437 | 0.75 | QPCTL (0.46) | NTRK1QPCTL | |
| SCHEMBL16790402 | 0.75 | PDE10A (0.83) | PDE10A | |
| Hydrochloric Acid SCHEMBL16765653 | 0.74 | PDE10A (0.82) | PDE10A | |
| SCHEMBL903276 | 0.73 | PARP1 (0.52) | QPCTPOLBSMN1; SMN2TDP1MMP12 | |
| Methylethylamine SCHEMBL4914029 | 0.72 | PARP1 (0.41) | QPCTPOLBSMN1; SMN2TDP1MMP12 | |
| SCHEMBL4625651 | 0.72 | SLC6A4 (0.49) | PKMPOLBHPGDMEN1ALDH1A1 | |
| SCHEMBL15825217 | 0.71 | MMP12 (0.45) | PDE10AQPCTDRD2TDP1MMP12 | |
| SCHEMBL8668924 | 0.71 | QPCT (0.46) | PDE10AQPCTPOLBHPGDSMN1; SMN2 | |
| SCHEMBL2542320 | 0.70 | QPCT (0.46) | QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720472-A | Benzimidazole compound, and preparation method and application thereof | 苏州沪云新药研发股份有限公司 | 2024-03-19 | — | — | CN | disclosed |