Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCT | Q16769 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 3/20 | 0.43 |
| ▸ | ACHE | P22303 | 3/20 | 0.43 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15979951 | 0.74 | CTNNB1 (0.65) | POLBTDP1KMT2AMAPTMEN1 | |
| SCHEMBL582321 | 0.73 | CA2 (0.54) | POLBGAAKMT2AMEN1ALDH1A1 | |
| SCHEMBL30848255 | 0.71 | PDE10A (0.48) | QPCTPOLBTDP1PDE10AKMT2A | |
| SCHEMBL29172092 | 0.71 | PDE10A (0.48) | QPCTPOLBTDP1PDE10AKMT2A | |
| SCHEMBL7986158 | 0.71 | POLB (0.66) | POLBBCHEACHEKDM4EALDH1A1 | |
| SCHEMBL1801614 | 0.69 | ALDH1A1 (0.77) | POLBTDP1KMT2AMAPTMEN1 | |
| SCHEMBL3630281 | 0.69 | QPCT (0.84) | QPCTGAAKMT2AMEN1L3MBTL1 | |
| SCHEMBL15980122 | 0.68 | CTNNB1 (0.62) | KMT2AKDM4EALDH1A1HPGDHTT | |
| SCHEMBL10406930 | 0.68 | ALDH1A1 (0.46) | POLBTDP1KMT2AMAPTMEN1 | |
| SCHEMBL11034493 | 0.67 | KDM4E (0.50) | QPCTPOLBTDP1CHEK2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830343-A1 | BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-03-25 | — | — | EP | claimed |
| WO-1996039390-A1 | BENZIMIDAZOLE DERIVATIVES AS INHIBITORS OF SMOOTH MUSCLE CELL PROLIFERATION | AMERICAN HOME PRODUCTS CORPORATION (US) | 1996-12-12 | — | — | WO | claimed |