Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | APEX1 | P27695 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | QPCT | Q16769 | 4/20 | 0.45 |
| ▸ | PRKCI | P41743 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PSMD11 | O00231 | 1/20 | 0.43 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | AHR | P35869 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.40 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.39 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrolidine SCHEMBL4767526 | 0.88 | PARP1 (0.42) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| Thiophene SCHEMBL28408804 | 0.88 | PARP1 (0.42) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| Piperidine SCHEMBL4768366 | 0.86 | PARP1 (0.41) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| Methylethylamine SCHEMBL4914029 | 0.86 | PARP1 (0.41) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL28178019 | 0.84 | PSMD11 (0.49) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL903277 | 0.83 | PRKCI (0.59) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL29488199 | 0.80 | TRPA1 (0.44) | PARP1MAPTKDM4EALDH1A1APEX1 | |
| SCHEMBL30848128 | 0.79 | IDO1 (0.51) | PARP1MAPTQPCTPOLBHTT | |
| SCHEMBL29172082 | 0.79 | IDO1 (0.51) | PARP1MAPTQPCTPOLBHTT | |
| SCHEMBL31143361 | 0.77 | MAPT (0.50) | MAPTKDM4EALDH1A1APEX1RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 240 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4200292-B1 | 1H-BENZO[D]IMIDAZOLE DERIVATIVES AS TLR9 INHIBITORS FOR THE TREATMENT OF FIBROSIS | BRISTOL MYERS SQUIBB CO (US) | 2024-11-13 | — | — | EP | claimed |
| CN-107955020-B | Method for synthesizing benzimidazol oxazinone compound by copper salt catalysis in one pot | 西南大学 | 2020-09-22 | — | — | CN | claimed |
| CN-107955020-A | The method of mantoquita catalysis one-pot synthesis benzimidazole and oxazine ketone compounds | 西南大学 | 2018-04-24 | — | — | CN | claimed |
| CN-105646366-B | The synthetic method of benzimidazole nitrence base class compound | 西南大学 | 2018-03-30 | — | — | CN | claimed |
| CN-105435744-A | Method for preparing zeolite-like imidazate framework material for adsorbing n-alkanes in naphtha | UNIV CHANGZHOU | 2016-03-30 | — | — | CN | claimed |
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| US-20110263610-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IRM LLC (BM) | 2011-10-27 | — | — | US | claimed |
| EP-0837096-B1 | PNEUMATIC TIRE | BRIDGESTONE CORP (JP) | 2004-02-18 | — | — | EP | claimed |
| JP-62061978-A | — | — | None | — | — | JP | disclosed |
| US-20260138071-A1 | SULFIDE GAS REMOVAL PROCESS | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2026-05-21 | — | — | US | disclosed |
| CN-122036621-A | Fluorine substituted benzimidazolyl aniline compound and synthetic method and application thereof | 中茂绿能科技(西安)有限公司 | 2026-05-15 | — | — | CN | disclosed |
| US-12544382-B2 | 2, 4, 6-tri-substituted pyrimidine compound as ATR kinase inhibitor | BEIJING TIDE PHARMACEUTICAL CO., LTD. (CN) | 2026-02-10 | — | — | US | disclosed |
| US-20260014197-A1 | DRUG DELIVERY SYSTEM | IMAM ABDULRAHMAN BIN FAISAL UNIVERSITY (SA) | 2026-01-15 | — | — | US | disclosed |
| US-20260014514-A1 | METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR | KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS (SA) | 2026-01-15 | — | — | US | disclosed |
| EP-0589649-A1 | A silver halide photographic light-sensitive material | KONICA CORPORATION (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5153116-A | Using a isothiazol-3-one or 1,2-benzoisothiazol-3-one compound in a layer also containing a spectral sensitizing dye; monochromatic films; negatives | KONICA CORPORATION (JP) | 1992-10-06 | — | — | US | disclosed |
| EP-0367243-A1 | A silver halide photographic light-sensitive material excellent in antistatic property | KONICA CORPORATION (JP) | 1990-05-09 | — | — | EP | disclosed |
| JP-S6261978-A | 5-FLUORO-1H-BENZIMIDAZOLE DERIVATIVE | OTSUKA PHARMACEUT CO LTD | 1987-03-18 | — | — | JP | disclosed |
| US-3935314-A | Anti-hypertensive compositions of benzimidazole derivatives | BEECHAM GROUP LIMITED (EN) | 1976-01-27 | — | — | US | disclosed |
| JP-S06261978-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110263610-A1 | COMPOUNDS AND COMPOSITIONS AS ITPKB INHIBITORS | IP6K1, IP6K2, IP6K3 | PARP1 2083/4885MAPT 3880/4885KDM4E 1856/4885 |
| US-20260138071-A1 | SULFIDE GAS REMOVAL PROCESS | SAMM50, SRSF1, GTF2F1 | PARP1 4288/4885MAPT 2949/4885KDM4E 2509/4885 |
| US-12544382-B2 | 2, 4, 6-tri-substituted pyrimidine compound as ATR kinase inhibitor | ATR, CHEK1, CHEK2 | PARP1 293/4885MAPT 3379/4885KDM4E 4066/4885 |
| US-20260014514-A1 | METHOD FOR SCAVENGING HYDROGEN SULFIDE FROM A GASEOUS COMPOSITION IN A STIRRED TANK REACTOR | SOD1, MAFG, HMOX2 | PARP1 4752/4885MAPT 3303/4885KDM4E 3342/4885 |
| US-20260014197-A1 | DRUG DELIVERY SYSTEM | IPO8, SLC39A11, SLC2A8 | PARP1 1130/4885MAPT 113/4885KDM4E 1719/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.