Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.61 |
| ▸ | CNR2 | P34972 | 1/20 | 0.61 |
| ▸ | CTSD | P07339 | 1/20 | 0.58 |
| ▸ | STAT3 | P40763 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.53 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20068936 | 0.89 | HCN1 (0.55) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL21652028 | 0.85 | CHRM5 (0.52) | FAAHCNR2CTSDSMN1; SMN2MEN1 | |
| SCHEMBL20147583 | 0.85 | HCN1 (0.57) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL20147987 | 0.85 | FAAH (0.50) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL30855446 | 0.83 | FAAH (0.59) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL30848550 | 0.79 | FAAH (0.56) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL30848628 | 0.79 | FAAH (0.56) | FAAHCNR2CTSDSTAT3RAB9A | |
| SCHEMBL30848467 | 0.78 | CNR2 (0.89) | FAAHCNR2CTSDSTAT3MEN1 | |
| SCHEMBL397839 | 0.78 | HPGD (0.51) | RAB9ANPC1SMN1; SMN2HPGDGAA | |
| SCHEMBL30848679 | 0.77 | CNR2 (0.64) | FAAHCNR2CTSDSTAT3RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |