Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.56 |
| ▸ | CNR2 | P34972 | 1/20 | 0.56 |
| ▸ | CTSD | P07339 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | STAT3 | P40763 | 1/20 | 0.50 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.49 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848469 | 0.81 | HPGD (0.46) | MAPTSMN1; SMN2NPC1RAB9AALDH1A1 | |
| SCHEMBL30848464 | 0.81 | CNR2 (0.60) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL30848613 | 0.79 | FAAH (0.61) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL30855446 | 0.78 | FAAH (0.59) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL30848511 | 0.77 | MEN1 (0.60) | CTSDKCNA3ALDH1A1MEN1KMT2A | |
| SCHEMBL30848679 | 0.75 | CNR2 (0.64) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL18284638 | 0.75 | HPGD (0.61) | CTSDSMN1; SMN2NPC1STAT3KCNK3 | |
| SCHEMBL30014039 | 0.74 | CNR2 (0.63) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL30848550 | 0.74 | FAAH (0.56) | FAAHCNR2CTSDMAPTSMN1; SMN2 | |
| SCHEMBL30848456 | 0.74 | HPGD (0.60) | CTSDSMN1; SMN2NPC1STAT3KCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |