Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TYK2 | P29597 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30848628 | 0.81 | FAAH (0.56) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL23777401 | 0.77 | NPC1 (0.50) | NPC1RAB9AMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL397839 | 0.77 | HPGD (0.51) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL31079661 | 0.75 | HPGD (0.46) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 | |
| SCHEMBL13193074 | 0.73 | HPGD (0.47) | HPGDNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL30848451 | 0.73 | HPGD (0.47) | HPGDNPC1RAB9ATP53SMN1; SMN2 | |
| SCHEMBL10279699 | 0.73 | NPC1 (0.48) | HPGDNPC1RAB9AMAPTSMN1; SMN2 | |
| SCHEMBL395687 | 0.72 | HPGD (0.58) | HPGDNPC1RAB9ATP53MAPT | |
| SCHEMBL13164041 | 0.72 | PYGL (0.54) | HPGDPOLB | |
| SCHEMBL10279697 | 0.72 | CTSL (0.48) | HPGDNPC1RAB9ASMN1; SMN2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | claimed |
| CN-118043327-A | FGFR inhibitors and methods of use thereof | 思康睿奇(上海)药业有限公司 | 2024-05-14 | — | — | CN | disclosed |