Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | TOP2A | P11388 | 6/20 | 0.47 |
| ▸ | DUT | P33316 | 1/20 | 0.42 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.36 |
| ▸ | TK1 | P04183 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2284865 | 0.87 | TOP2A (0.57) | TOP2ADUTBCHEHDAC1TK1 | |
| SCHEMBL10046512 | 0.85 | TOP2A (0.47) | TOP2ADUTBCHEHDAC1TK1 | |
| SCHEMBL12373095 | 0.83 | TOP2A (0.47) | TOP2ADUTBCHEHDAC1TK1 | |
| SCHEMBL9222583 | 0.81 | LMNA (0.69) | LMNAALOX12ADRA1ASMN1; SMN2TOP2A | |
| SCHEMBL9222577 | 0.81 | LMNA (0.69) | LMNAALOX12ADRA1ASMN1; SMN2TOP2A | |
| SCHEMBL9706042 | 0.80 | LMNA (0.49) | LMNAALOX12ADRA1ASMN1; SMN2BCHE | |
| SCHEMBL9221567 | 0.80 | LMNA (0.54) | LMNAALOX12ADRA1ASMN1; SMN2TOP2A | |
| SCHEMBL9706045 | 0.80 | LMNA (0.53) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL2041288 | 0.80 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL19493129 | 0.80 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720603-B | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-05-03 | — | — | CN | disclosed |
| CN-117720603-A | Synthesis method and application of 5-trifluoromethyl-2 ',3' -dideoxyuridine-5 ' -triphosphate | 天津奥利芙生物技术有限公司 | 2024-03-19 | — | — | CN | disclosed |