Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TK1 | P04183 | 4/20 | 0.45 |
| ▸ | TYMS | P04818 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | POLD1 | P28340 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9706045 | 0.92 | LMNA (0.53) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL27389186 | 0.88 | POLB (0.50) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL9706074 | 0.86 | POLB (0.53) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL13245040 | 0.86 | TK1 (0.57) | TK1POLBPOLA1POLD1BCHE | |
| SCHEMBL2041288 | 0.81 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL9706055 | 0.81 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL19493129 | 0.81 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL30848702 | 0.80 | LMNA (0.47) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL21277491 | 0.79 | LMNA (0.58) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL6420653 | 0.79 | TK1 (0.58) | TK1POLBPOLA1POLD1BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507188-A1 | Substituted 2',3'-dideoxy-5-trifluoromethyluridines, method of their preparation and their use in medicaments | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |