Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.53 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | TK1 | P04183 | 4/20 | 0.51 |
| ▸ | TYMS | P04818 | 4/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27389186 | 0.92 | POLB (0.50) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL9706042 | 0.92 | LMNA (0.49) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL9706074 | 0.90 | POLB (0.53) | LMNAALOX12ADRA1ASMN1; SMN2TK1 | |
| SCHEMBL15713242 | 0.86 | TK1 (0.53) | LMNASMN1; SMN2TK1TYMS | |
| SCHEMBL23440065 | 0.84 | TK1 (0.67) | TK1TYMS | |
| SCHEMBL26757571 | 0.84 | TK1 (0.67) | TK1TYMS | |
| SCHEMBL28774920 | 0.84 | TK1 (0.67) | TK1TYMS | |
| SCHEMBL8883 | 0.84 | TK1 (0.67) | TK1TYMS | |
| SCHEMBL19389398 | 0.84 | TK1 (0.52) | SMN1; SMN2TK1TYMS | |
| SCHEMBL19493129 | 0.83 | LMNA (0.64) | LMNAALOX12ADRA1ASMN1; SMN2TK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507188-A1 | Substituted 2',3'-dideoxy-5-trifluoromethyluridines, method of their preparation and their use in medicaments | BAYER AG (DE) | 1992-10-07 | — | — | EP | disclosed |