SCHEMBL3084919

SCHEMBL3084919

CC(=O)OCc1ccc(C(=O)NNC(=O)c2ccc(C(C)(C)C)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.58
POLB P06746 1/20 0.57
ESRRG P62508 2/20 0.56
ALDH1A1 P00352 3/20 0.55
EPHX2 P34913 5/20 0.54
NR1H4 Q96RI1 4/20 0.54
RAB9A P51151 2/20 0.53
NR4A2 P43354 1/20 0.52
RXRA P19793 1/20 0.52
RXRB P28702 1/20 0.52
ESRRB O95718 1/20 0.51
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
HDAC1 Q13547 2/20 0.50
NPC1 O15118 1/20 0.50
HDAC3 O15379 1/20 0.50
HDAC2 Q92769 1/20 0.50
HDAC8 Q9BY41 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2092731 0.90 ALDH1A1 (0.60) MAPTESRRGALDH1A1EPHX2NR1H4
SCHEMBL6728402 0.82 ALDH1A1 (0.49) MAPTALDH1A1RAB9ARXRARXRB
SCHEMBL14438185 0.81 POLB (0.81) MAPTPOLBESRRGALDH1A1RAB9A
SCHEMBL11738359 0.81 SMN1; SMN2 (0.54) MAPTPOLBESRRGALDH1A1EPHX2
SCHEMBL10392942 0.80 KMT2A (0.65) MAPTESRRGALDH1A1RAB9ANR4A2
SCHEMBL13411551 0.80 PLK1 (0.59) ALDH1A1EPHX2NR1H4RAB9AMEN1
SCHEMBL3082525 0.80 RAB9A (0.62) MAPTPOLBALDH1A1EPHX2NR1H4
SCHEMBL1788828 0.78 SMN1; SMN2 (0.56) MAPTESRRGALDH1A1RAB9ANR4A2
SCHEMBL132773 0.77 ALDH1A1 (0.78) MAPTPOLBALDH1A1MEN1KMT2A
SCHEMBL11701842 0.77 ALDH1A1 (0.56) MAPTALDH1A1NR4A2RXRARXRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
EP-2258804-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2010-12-08 EP disclosed
US-7795802-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2010-09-14 US disclosed
US-7365141-B2 Solvent resistance; luminescent film-forming solvent processible polymer which contains cross-linking so as to increase its molar mass and to resist solvent dissolution, the cross-linking being such that the polymer retains semiconductive and luminescent properties; capable of charge transport CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2008-04-29 US disclosed
EP-1801181-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2007-06-27 EP disclosed
EP-1715021-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
EP-1715020-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
US-7105621-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-09-12 US disclosed
US-20060151782-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-07-13 US disclosed
EP-1291406-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2006-06-21 EP disclosed
EP-1006169-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2004-11-03 EP disclosed
US-6723811-B1 PHOTOLUMINESCENT AND ELECTROLUMINESCENT DEVICES; SEMICONDUCTOR POLYMER; ORGANIC LED; CROSSLINKING TO MAKE INSOLUBLE CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-04-20 US disclosed
US-20030166810-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-09-04 US disclosed
US-6559256-B2 Luminescent film-forming solvent processible polymer for use in photoluminescent and electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-05-06 US disclosed
EP-1291406-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2003-03-12 EP disclosed
US-20030008991-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-01-09 US disclosed
EP-0800563-B1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2000-07-12 EP disclosed
EP-1006169-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2000-06-07 EP disclosed
EP-0800563-A1 POLYMERS FOR USE IN OPTICAL DEVICES Cambridge Display Technology Limited (GB) 1997-10-15 EP disclosed
WO-1996020253-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 1996-07-04 WO disclosed