SCHEMBL3082525

SCHEMBL3082525

CC(=O)OCc1ccc(C(=O)NNC(=O)c2ccc(-c3ccccc3)cc2)cc1

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 4/20 0.62
ALDH1A1 P00352 4/20 0.62
CTDSP1 Q9GZU7 3/20 0.62
NPC1 O15118 3/20 0.62
MAPT P10636 4/20 0.59
KMT2A Q03164 5/20 0.56
MEN1 O00255 3/20 0.56
TP53 P04637 1/20 0.56
HPGD P15428 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
POLB P06746 5/20 0.52
HDAC3 O15379 1/20 0.51
HDAC1 Q13547 1/20 0.51
HDAC2 Q92769 1/20 0.51
HDAC8 Q9BY41 1/20 0.51
NCOR2 Q9Y618 1/20 0.51
CYP3A4 P08684 1/20 0.51
EPHX2 P34913 1/20 0.50
NR1H4 Q96RI1 1/20 0.50
ADAMTS4 O75173 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL487227 0.89 ALDH1A1 (0.78) RAB9AALDH1A1NPC1MAPTKMT2A
Biphenyl SCHEMBL11403488 0.84 ALDH1A1 (0.88) RAB9AALDH1A1NPC1MAPTKMT2A
SCHEMBL20326231 0.82 ALDH1A1 (0.61) RAB9AALDH1A1NPC1MAPTKMT2A
SCHEMBL4198688 0.82 ALDH1A1 (0.69) RAB9AALDH1A1NPC1MAPTKMT2A
SCHEMBL13014111 0.81 ALDH1A1 (0.57) RAB9AALDH1A1NPC1MAPTKMT2A
SCHEMBL14063393 0.80 ALDH1A1 (0.64) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL9581057 0.80 ALDH1A1 (0.64) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL14063398 0.80 ALDH1A1 (0.64) RAB9AALDH1A1NPC1MAPTHPGD
SCHEMBL3084919 0.80 MAPT (0.58) RAB9AALDH1A1NPC1MAPTKMT2A
SCHEMBL13411551 0.79 PLK1 (0.59) RAB9AALDH1A1NPC1KMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2258804-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2012-08-22 EP disclosed
EP-2258804-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2010-12-08 EP disclosed
US-7795802-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2010-09-14 US disclosed
US-7365141-B2 Solvent resistance; luminescent film-forming solvent processible polymer which contains cross-linking so as to increase its molar mass and to resist solvent dissolution, the cross-linking being such that the polymer retains semiconductive and luminescent properties; capable of charge transport CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2008-04-29 US disclosed
EP-1801181-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2007-06-27 EP disclosed
EP-1715021-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
EP-1715020-A2 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2006-10-25 EP disclosed
US-7105621-B2 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-09-12 US disclosed
US-20060151782-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2006-07-13 US disclosed
EP-1291406-B1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECH LTD (GB) 2006-06-21 EP disclosed
US-6723811-B1 PHOTOLUMINESCENT AND ELECTROLUMINESCENT DEVICES; SEMICONDUCTOR POLYMER; ORGANIC LED; CROSSLINKING TO MAKE INSOLUBLE CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-04-20 US disclosed
US-20040059077-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2004-03-25 US disclosed
US-20030166810-A1 Polymers for use in optical devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-09-04 US disclosed
US-6559256-B2 Luminescent film-forming solvent processible polymer for use in photoluminescent and electroluminescent devices CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 2003-05-06 US disclosed
EP-1291406-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2003-03-12 EP disclosed
US-20030008991-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2003-01-09 US disclosed
EP-0800563-B1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECH LTD (GB) 2000-07-12 EP disclosed
EP-1006169-A1 Polymers for use in optical devices Cambridge Display Technology Limited (GB) 2000-06-07 EP disclosed
EP-0800563-A1 POLYMERS FOR USE IN OPTICAL DEVICES Cambridge Display Technology Limited (GB) 1997-10-15 EP disclosed
WO-1996020253-A1 POLYMERS FOR USE IN OPTICAL DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LTD. (GB) 1996-07-04 WO disclosed