Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 13/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30849242 | 0.78 | EPHX1 (0.40) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL30892902 | 0.77 | MEN1 (0.33) | — | |
| SCHEMBL32678639 | 0.77 | EPHX1 (0.44) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL32678640 | 0.77 | EPHX1 (0.44) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL32678641 | 0.77 | EPHX1 (0.44) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL21250185 | 0.75 | EPHX1 (0.42) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL30292346 | 0.69 | EPHX1 (0.42) | EPHX1ACHEALDH1A1ATM | |
| SCHEMBL16166336 | 0.69 | ACHE (0.57) | EPHX1ACHEEPHX2 | |
| SCHEMBL30354527 | 0.68 | ACHE (0.60) | EPHX1ACHEEPHX2 | |
| SCHEMBL22234039 | 0.67 | CHRM1 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4598908-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | Pfizer Inc. (US) | 2025-08-13 | — | — | EP | disclosed |
| WO-2024075051-A1 | HSD17B13 INHIBITORS AND/OR DEGRADERS | PFIZER INC. (US) | 2024-04-11 | — | — | WO | disclosed |